JULIANNA MARGULIES (SNAKES ON A PLANE) - Interview

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When a young man (Nathan Phillips) witnesses a brutal mob murder, it falls to FBI agent Neville Flynn (Samuel L. Jackson) to escort his charge safely from Hawaii to Los Angeles to testify.

But in an act of self-preservation, the crime boss facing prison smuggles hundreds of poisonous snakes onto the commercial aircraft in a crate timed to release its deadly cargo halfway over the Pacific.

Flynn, along with a frightened flight crew and passengers, must then band together in a desperate attempt to survive.